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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
14.5 DPC

9 matching records from 9 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Atoh1  atonal bHLH transcription factor 1   (Synonyms: bHLHa14, Hath1, Math1)
Results  Reference
1*J:181471 Ahmed M, Wong EY, Sun J, Xu J, Wang F, Xu PX, Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90
1J:152710 Aldinger KA, Lehmann OJ, Hudgins L, Chizhikov VV, Bassuk AG, Ades LC, Krantz ID, Dobyns WB, Millen KJ, FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation. Nat Genet. 2009 Sep;41(9):1037-42
1J:200759 Bok J, Zenczak C, Hwang CH, Wu DK, Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13869-74
1J:206577 Green MJ, Myat AM, Emmenegger BA, Wechsler-Reya RJ, Wilson LJ, Wingate RJ, Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1. Development. 2014 Jan;141(2):389-98
1J:242970 Jahan I, Pan N, Kersigo J, Calisto LE, Morris KA, Kopecky B, Duncan JS, Beisel KW, Fritzsch B, Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival. PLoS One. 2012;7(1):e30853
1J:220948 Jahan I, Pan N, Kersigo J, Fritzsch B, Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea. PLoS One. 2010;5(7):e11661
1J:191198 Kopecky BJ, Jahan I, Fritzsch B, Correct Timing of Proliferation and Differentiation is Necessary for Normal Inner Ear Development and Auditory Hair Cell Viability. Dev Dyn. 2013 Feb;242(2):132-47
1*J:85727 Louvi A, Alexandre P, Metin C, Wurst W, Wassef M, The isthmic neuroepithelium is essential for cerebellar midline fusion. Development. 2003 Nov;130(22):5319-30
1*J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory